hrp0089lb-p6 | Late Breaking P1 | ESPE2018

Sex Hormone Levels in Young Children: a Pilot Study of the Japan Environment and Children’s Study

Ayabe Tadayuki , Fukami Maki , Yamamoto-Hanada Kiwako , Ishitsuka Kazue , Mezawa Hidetoshi , Konishi Mizuho , Saito Mayako , Sasaki Hatoko , Satoh Miori , Nishizato Minaho , Michikawa Takehiro , Yamazaki Shin , Monden Yukifumi , Mise Nathan , Kayama Fujio , Shimono Masayuki , Kusuhara Koichi , Kawamoto Toshihiro , Sanefuji Masafumi , Kato Kiyoko , Oda Masako , Mitsubuchi Hiroshi , Katoh Takahiko , Saito Hirohisa , Ohya Yukihiro

Background: Information on sex hormone levels in young children is currently lacking, because those levels are generally below the lower limit of quantitation of conventional immunoassay methods. We investigated sex differences in serum levels of sex hormones in relation to upstream hormones and other background factors in young children, using liquid chromatography-tandem mass spectrometry (LC-MS/MS).Methods: This cross-sectional study enrolled 151 chil...